Today, let us focus on Methotrexate; the king of DMARDs. Yes, you heard it right.. The King. It has been crowned the king by Rheumies, Scientists & patients alike.
· Rheumatologists- it is the most frequently prescribed DMARD for Rheumatoid Arthritis (RA) across the globe.
· Scientists – Most studies of biologics include patients who are not responding to Methotrexate, underlying its role as the most important DMARD.
· Patients- Studies have shown that patients continue Methotrexate longer than any other DMARD; thus making it the most tolerated DMARD.
So, if you have RA & are on Methotrexate, be rest assured that you are with the King. You are taking the world’s most trusted DMARD.
For the newly diagnosed, someone may scare you that Methotrexate is a cancer medication. Yes it is; but in a very high dose as compared to that for RA. Just the way salt is used in many dishes, even drugs like Methotrexate are used in many different conditions. And, mind you, RA is akin to cancer. The swollen rogue synovium proliferates like a cancer tissue & eats up the cartilage & bones. Methotrexate works against these rogue cells, be it cancer or RA.
This is just the glimpse of the King.
Probably, I’ve hyped a bit. Shortly, we’ll have a look at the effects on RA & the side effects to decide whether it is really toxic.